Category Archives: Non classé

We have introduced in lipoplexes a Hyaluronic acid-phospholipid conjugate. The modified lipoplexes were able to target specifically MDA-MB 231 cells expressing CD44  receptor. Transfection was blocked by antiCD44 antibody. This system open up interesting properties in the design of targeted delivery of DNA to … Continue reading →

In collaboration with Lori Bridal & Wladimir Urbach  and Brigitte Gillet, with my young colleague Nicolas Tsapis, we have applied nanotechnologies containg pefluoroctylbromide previously described for ultrasound imaging and 19F MRI. An animal experiment carried out on nude mice show a … Continue reading →

We have designed Pectin beads containing -lactamases for the hydrolysis of colonic residual antibiotics responsible for the emergence of resistance. In previous experiments, beads were  shown to increase the level of active beta lactamases in the feces. We now show that … Continue reading →