Monthly Archives: May 2009
Lipoplexes targeting the CD 44 receptor
We have introduced in lipoplexes a Hyaluronic acid-phospholipid conjugate. The modified lipoplexes were able to target specifically MDA-MB 231 cells expressing CD44 receptor. Transfection was blocked by antiCD44 antibody. This system open up interesting properties in the design of targeted delivery of DNA to … Continue reading
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